Platelet Dysfunctions and Rare Bleeding Disorders
CHS has descriptions of platelet function disorders that includes more information on the following:
Disorder of platelet adhesion – Bernard-Soulier Syndrome
It is caused by a deficiency on the surface of the platelet in an area called Glycoprotein Ib/IX. As a result, platelets fail to stick and clump together at the site of the injury.
Disorder of platelet aggregation – Glanzmann thrombasthenia
It is caused by a deficiency of a protein on the surface of the platelet, called Glycoprotein IIb/IIIa. As a result, platelets fail to form a plug at the site of an injury.
Storage Pool Deficiencies are a group of disorders caused by problems with platelet granules.
Disorders of platelets procoagulant activity – Scott syndrome
Combined abnormalities of number and function
More information about platelet function disorders can be found via the following websites:
Types of platelet function disorders | Hemophilia
WFH eLearning Platform – Inherited Platelet Disorders
Rare Factor Deficiencies
Less than 1.000 Canadians, suffer from rare factor deficiencies. They have low levels of a specific blood protein, either factor I, II, V, VII, X, XI or XIII.
For more information, please visit:
Rare factor deficiencies | Hemophilia